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Biography

Yanshan Wang’s research centers on health informatics and clinical research informatics. He develops innovative methodologies using artificial intelligence (AI), specifically natural language processing (NLP) techniques to serve the needs of patients, physicians and researchers using electronic health records (EHRs), particularly free-text EHRs. Wang has collaborated with clinicians and researchers to create multiple NLP algorithms that extract meaningful information from clinical notes. These novel NLP approaches have been applied in areas such as Alzheimer’s disease, mental health disorders, cancer phenotyping and social determinants of health.

Wang is involved in various NIH-funded projects aimed at creating advanced clinical NLP algorithms and infrastructures to support clinical and translational research. Notably, he serves as the NLP Lead for the ENACT Network funded by NCATS, which disseminates NLP infrastructure to 57 CTSA hubs. He also leads the development of the Rehabilitation Datamart with Informatics Infrastructure for Research (ReDWINE), designed to streamline EHR data access and enhance informatics tools for rehabilitation research at SHRS.

Currently, Wang leads the Clinical Natural Language Processing and Artificial Intelligence Innovation Laboratory (PittNAIL). PittNAIL focuses on cutting-edge technologies in AI and NLP for health care applications, pioneering the use of generative AI and large language models (LLMs) in clinical NLP. The lab is among the first to use these LLMs in zero-shot and few-shot settings for clinical purposes. Recently, their research has expanded to evaluate generative AI models and assess the impact of generative AI in health care, particularly its ethical implications. Wang is the original author of the GREAT PLEA ethical principles for using generative AI in health care.

Awards
  • 2020 Fellows of AMIA (FAMIA)
Research Interests
  • Artificial intelligence (AI)
  • Natural language processing (NLP)
  • Machine/deep learning methodologies
Publications
  • Oniani D, Hilsman J, Peng Y, Poropatich RK, Pamplin JC, Legault GL, Wang Y. Adopting and expanding ethical principles for generative artificial intelligence from military to healthcare. NPJ Digital Medicine. 2023.
  • Sivarajkumar S, Huang Y, Wang Y. Fair patient model: Mitigating bias in the patient representation learned from the electronic health records. Journal of Biomedical Informatics. 2023.
  • Y Wang, X Wu, L Carlson, D Oniani . Generative AI enhanced with NCCN clinical practice guidelines for clinical decision support: A case study on bone cancer. Journal of Clinical Oncology. 2024.
Professional Organization Appointments
  • Chair of the AMIA Natural Language Processing Working Group
  • Reviewer for prestigious journals, such as Nature Communications, Bioinformatics, Journal of the American Medical Informatics Association (JAMIA), Journal of Biomedical Informatics (JBI) and IEEE Transactions on Knowledge and Data Engineering (TKDE)
  • Organizers and PC members for health informatics conferences, such as AMIA, ACM-BCB, IEEE-ICHI, and IEEE-BIBM